Identification of a tuberculosis infection (TB) is essential to prevent the spread of this contagious bacterial disease, typically transmitted through the air. While some individuals with inactive TB may not exhibit any symptoms, others may have an active form of TB. It is important to note that those with latent TB are not capable of transmitting the infection.
Tuberculosis testing involves various methods to detect the presence of the TB bacteria in the body. The most common test is the Mantoux tuberculin skin test, where a small amount of tuberculin protein is injected under the skin to see if there is a reaction. Another method is the TB blood test, which looks for the presence of antibodies produced in response to TB infection.
Chest X-rays and sputum tests are also used to diagnose TB, especially in individuals who exhibit symptoms such as coughing, chest pain, and weight loss. Treatment for TB typically involves a combination of antibiotics taken for several months to ensure the complete eradication of the bacteria.
Early detection and treatment of tuberculosis infection are crucial in preventing the spread of the disease to others and managing the symptoms effectively. It is important to consult a healthcare provider if you suspect you have been exposed to TB or are experiencing symptoms related to the infection.
When to Consider TB Testing
Individuals may need to undergo TB testing if they have been in contact with someone infected with TB or if their healthcare provider suspects an infection. Symptoms such as weight loss, coughing up blood, and shortness of breath may indicate the need for testing. Other factors, such as residing or working in high-risk TB areas or pregnancy, can also prompt the need for testing.
It is essential to emphasize the importance of early detection and treatment of TB to prevent the spread of the disease. TB can be effectively treated with antibiotics, especially when diagnosed early. Regular testing and monitoring are crucial for individuals at high risk of TB exposure to ensure prompt diagnosis and appropriate care.
Interpreting TB Skin Test Results
If a skin test reveals a positive result, further testing is required to confirm whether the infection is active or latent TB. Importantly, a positive skin test does not necessarily mean an immediate infection, as inactive TB can be controlled by a strong immune system. Conversely, a negative result does not definitively rule out infection and may necessitate further testing for confirmation.
Considerations for Vaccinated Individuals
Individuals who have received the Bacilli Calmette-Guerin vaccine may show positive results on a skin test. It is important to consider other factors, such as medications or supplements, that can influence the accuracy of the test results. While no special preparation is required for the test, it is crucial to inform your healthcare provider about any relevant medications or supplements.
Utilizing the TB blood test, known as Interferon Gamma Release Assay or IGRA, can effectively detect TB bacteria in the body. This test serves as an alternative to the TB skin test and is recommended in specific circumstances. Two variations of TB blood tests are currently available: QuantiFERON-TB and T-SPOT.TB.
Benefits of TB Blood Tests:
- Provide more accurate and specific results compared to the TB skin test.
- Do not cross-react with the Bacilli Calmette-Guerin vaccine, reducing the likelihood of false positive results.
- Require a single blood draw, making it a more convenient option for individuals.
It is important to consult with your healthcare provider to determine the most appropriate TB testing method based on your individual circumstances and medical history.
Individuals at High Risk for TB Infection
- Close contact with active TB patients
- Residence in regions with a high prevalence of TB
- Occupation in medical or communal settings
- Immune-compromised individuals
Children under the age of 2 should opt for the skin test instead. Consulting your healthcare provider regarding the blood test procedure and potential results is crucial.
Understanding TB Test Results
Negative results from TB testing indicate the absence of TB bacteria, while positive results suggest a probable TB infection. Further examinations and tests are necessary for confirmation and to establish a treatment plan.
It is important to follow up with healthcare providers if you have positive TB test results. Treatment for TB infection usually involves taking antibiotics for several months to kill the bacteria and prevent the development of active TB disease.
Additionally, it is important to follow infection control measures to prevent the spread of TB to others. This may include covering your mouth when coughing, staying home when you are sick, and avoiding close contact with others until you are no longer contagious.
Addressing Different Stages of TB
Tuberculosis exists in two stages – latent infection and active disease, both of which can be effectively treated with appropriate medications. It is important to note that latent TB has the potential to progress into active TB without treatment. While vaccines offer protection, their effectiveness may decline over time.
When faced with a decision between TB tests following BCG vaccination, the blood test emerges as a more dependable option. Prioritize your health and that of your loved ones by undergoing testing.
- Download PDF version formatted for print:
TB Skin Test (Mantoux) (PDF)
The TB skin test, also known as “Mantoux,” is a non-invasive screening method designed to detect latent TB infection.
Completing a TB Skin Test
A TB skin test is designed to identify latent infection, particularly after exposure to individuals with active TB. After a small amount of tuberculin is injected under the skin, the area is assessed for any reactions within 2-3 days.
- Do not apply any lotions or creams to the injection site as they may interfere with the results of the test
- Avoid strenuous exercise or activities that may cause excessive sweating as it could irritate the injection site
- If you experience any redness, swelling, or increasing pain at the injection site, contact your healthcare provider immediately
- Keep the injection site clean and dry to prevent infection
- Make sure to follow up with your healthcare provider for the results of the TB skin test
It is important to note that a negative TB skin test does not necessarily mean that a person is not infected with TB, as the test may not always be accurate. If you have been in close contact with someone who has active TB, if you have HIV/AIDS, or if you have other risk factors for TB infection, it is important to discuss further testing options with your healthcare provider.
In some cases, a positive TB skin test may also be due to previous vaccination with the Bacille Calmette-Guerin (BCG) vaccine. Your healthcare provider will take these factors into consideration when interpreting your TB skin test results.
If you have a positive TB skin test, further testing such as a chest x-ray and possibly sputum samples may be recommended to confirm an active TB infection. Treatment for TB infection or disease may be necessary depending on the results of these additional tests.
Understanding Positive TB Skin Test Results
A positive test outcome signifies the presence of TB bacteria in the body. In most cases, individuals with positive results have latent TB infection, which can be confirmed through further testing and chest x-rays. Additional tests may be required to check for active TB disease.
To prioritize your health and that of your loved ones, consider undergoing a TB skin test. Reach out to your healthcare provider or local public health department to arrange testing.
Undergoing testing and receiving treatment for TB are critical for your well-being, as well as the health of your family, friends, and community.
Instances where a TB test may be necessary include:
- Exposure to individuals with active TB disease
- Requirements for employment, school, travel, or immigration-related health screenings
Even if you feel well, it is important to prioritize your health by undergoing testing, as TB can remain in the body without presenting noticeable symptoms.
It is important to note that the most common TB test is the Mantoux tuberculin skin test, which involves injecting a small amount of tuberculin under the skin of the forearm and checking for a reaction within 48 to 72 hours. Another test is the interferon-gamma release assay (IGRA), which is a blood test that detects TB infection by measuring the immune response to TB bacteria. Both tests can help detect TB infection early and prevent the development of active TB disease.
If you fall into any of the high-risk categories mentioned above, it is recommended to consult with a healthcare provider about getting tested for TB. Early detection and treatment are essential for managing TB infection and preventing the spread of the disease to others.
Types of TB Detection Tests
Two primary testing methods are used to detect TB infection: blood tests and skin tests. Consulting your healthcare provider is essential to determine the most appropriate test for your situation.
Blood Tests for TB Infection
Blood tests (IGRAs) detect TB infection by measuring the immune response to TB proteins within a blood sample.
Considerations for BCG Vaccinated Individuals
Individuals who have received the BCG vaccine should opt for blood tests over skin tests, as they are not influenced by the vaccine.
Skin Tests for TB Detection

Skin tests involve injecting testing material into the skin and evaluating the reaction after a few days.
Follow-Up Testing Based on Results
Further testing, such as chest x-rays and sputum analysis, is conducted depending on blood or skin test outcomes to confirm the presence of inactive or active TB.
Healthcare providers or public health departments typically offer TB testing services. Coverage for testing costs may be available under health insurance plans.
Interpreting Test Results
Additional Information on TB Testing
Ensuring timely testing and treatment for TB is crucial for maintaining your health, as well as the well-being of your loved ones.
Do not hesitate to seek TB testing in the following scenarios:
- Exposure to individuals with active TB disease
- Requirements for employment, school, travel, or immigration health screenings
Even in the absence of symptoms, undergoing testing is essential, as TB can persist in the body without causing visible signs.
Assessing High-Risk Individuals for TB Testing

Individuals with an elevated risk of TB infection are encouraged to undergo testing if exposure to TB bacteria is suspected. Factors that increase exposure risk include:
- Residence in or frequent travel to countries with a high TB prevalence
- Living in crowded environments where TB is prevalent
- Close contact with individuals with active TB
- Occupation in settings with a high likelihood of TB transmission
While some individuals with latent TB never progress to the disease, others may develop TB symptoms if their immune system weakens.
Individuals with weakened immune systems, recent TB exposure, children, illicit drug users, or those with underlying health conditions may have a higher risk of developing TB disease.
For individuals at a low risk of TB infection, routine testing may not be necessary.
Additional Information:
- It is important for high-risk individuals to undergo regular screening tests for TB to monitor their health status.
- TB testing methods include chest x-rays, tuberculin skin tests (TST), and interferon gamma release assays (IGRAs).
- Early detection of TB infection can help prevent the spread of the disease to others and ensure prompt treatment for the individual.
- Healthcare providers can provide guidance on the appropriate testing schedule based on individual risk factors and exposure history.
Utilizing Different Testing Methods for TB Infection
There are two primary testing methods employed to identify TB infection: blood tests and skin tests. Consulting with your healthcare provider is crucial to determine the most suitable test for your circumstances.
Types of Tests for TB Infection
Blood tests (IGRAs) detect TB infection by measuring the immune response to TB proteins in a blood sample.
Considerations for BCG Vaccinated Individuals
Individuals who have received the BCG vaccine are advised to opt for blood tests over skin tests, as the vaccine does not affect blood test results.
Skin Tests for TB Detection
Skin tests involve the injection of testing material into the skin, with the reaction being assessed after several days.
Follow-Up Testing Post Blood or Skin Test
Depending on the results of blood or skin tests, additional testing such as chest x-rays and sputum analysis may be required to determine the presence of inactive or active TB.
Healthcare providers or public health departments typically provide TB testing services, with coverage for testing expenses potentially available through health insurance plans.
Interpreting Test Results
Additional Steps Following Positive and Negative Test Results
If your TB test yields a positive result, further tests will be conducted to ascertain the presence of inactive or active TB bacteria.
A negative test outcome does not rule out TB infection, particularly if symptoms are present or if you are at an increased risk.
Lambton Public Health offers TB skin tests for medical purposes with adequate documentation. Contact them to determine eligibility and schedule appointments.
For employment or school-related purposes, primary healthcare providers or workplace occupational health services can conduct tests. Lambton College students should consult the Student Wellness Center.
Facilities Offering TB Testing Services:
Bayshore Home Health Sarnia
SMG Pharmacy
St. Clair Physician Group
The London Travel Clinic
Learn More about TB
TB Infection and TB Disease
Both TB infection and disease can be effectively treated with antibiotics. Public Health provides accessible treatment options.
Visit Canada.ca for comprehensive information on TB symptoms and treatment.
TB Skin Testing
TB screening involves a skin test to identify exposure. Follow-up care is arranged in case of a positive test.
One-step and two-step skin tests are available, with the latter establishing baselines.
Further two-step testing is unnecessary once documented, unless symptoms appear or exposure reoccurs.
Positive TB Skin Tests
A positive tuberculin skin test could indicate the presence of TB bacteria in the body. Public Health Nurses facilitate follow-up tests, such as blood work (IGRA) or referral to a Respirologist for treatment or monitoring. Reach out to Lambton Public Health at 160 Exmouth Street, Point Edward, ON N7T 7Z6.